Arginase Flavonoid Anti-Leishmanial in Silico Inhibitors Flagged against Anti-Targets
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چکیده
منابع مشابه
Arginase Flavonoid Anti-Leishmanial in Silico Inhibitors Flagged against Anti-Targets.
Arginase, a drug target for the treatment of leishmaniasis, is involved in the biosynthesis of polyamines. Flavonoids are interesting natural compounds found in many foods and some of them may inhibit this enzyme. The MetIDB database containing 5667 compounds was screened using an EIIP/AQVN filter and 3D QSAR to find the most promising candidate compounds. In addition, these top hits were scree...
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ژورنال
عنوان ژورنال: Molecules
سال: 2016
ISSN: 1420-3049
DOI: 10.3390/molecules21050589